Ace the Case: A 65-Year-Old Man with a History of Diabetes Mellitus, Hypertension, and Dyslipidemia
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Summary and References
Randomized clinical trials have demonstrated a benefit of lowering blood pressure to <140 mm Hg systolic and <90 mm Hg diastolic in individuals with diabetes. Lowering of blood pressure with regimens based on a variety of antihypertensive agents, including ACE inhibitors, ARBs, diuretics, and calcium channel blockers, has been shown to be effective in reducing cardiovascular events. Patients with T2DM have an increased prevalence of lipid abnormalities that contribute to a higher risk of CVD. Loop diuretics are useful in the treatment of edema due to heart failure, liver disease, and kidney disease. Multiple clinical trials have demonstrated the beneficial effects of pharmacologic therapy with statins on cardiovascular outcomes in patients with and without CVD.
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