Eosinophilic Esophagitis: Recent Developments in the Therapeutic Landscape – A GameOn! Challenge

Author(s)/Faculty: Evan S. Dellon, MD, MPH; Ikuo Hirano, MD, FACG
Release Date: 9/30/2022Expiration Date: 9/29/2023
Credit Type: CMENumber of Credits: 0.5
Content Type: GamingProvider:
Eosinophilic esophagitis (EoE) is a chronic type 2 helper (Th2)–mediated inflammatory disorder that affects both children and adults. It is characterized by symptoms of esophageal dysfunction and esophageal inflammation with intraepithelial eosinophils. Once considered rare, EoE is a relatively new disease that is now commonplace. When left unmanaged, EoE can impact a patient’s ability to eat properly, leading to food impaction and increased medical expenses. Real-world data indicate that many patients with EoE switch therapy frequently, demonstrating an unmet need for adequate control of disease-related symptoms. Many gastroenterologists and other relevant providers lack an understanding of the pathogenesis, guideline-based diagnostic criteria, and newly approved and emerging treatment options for EoE. These knowledge deficits may therefore exacerbate delays in diagnoses and, consequently, appropriate management. In this CME activity, participants will play the GameOn! Challenge, an interactive quiz of knowledge and confidence, in which they answer questions about management of patients with EoE, then select the level of confidence in their answers to achieve the highest score among their peers. Expert clinicians will review the pathogenesis and best practices for accurate diagnosis of EoE. They will also explore current treatment guidelines and the clinical data supporting the use of recently approved and emerging therapies for EoE.