GlaucomaCME
LECTURECME

Nitric Oxide Signaling and Its Effect on Outflow Pathways in Glaucoma

Author(s)/Faculty: Thomas W. Samuelson, MD; John P. Berdahl, MD
Release Date: 7/19/2019Expiration Date: 7/18/2020
Credit Type: CMENumber of Credits: 0.5
Content Type: LectureProvider:
Traditional medical therapy in glaucoma is directed to either reduction of aqueous humor production or improvement of aqueous outflow via the uveoscleral or unconventional pathway. However, these medications do little to restore function in the primary route of aqueous outflow, the conventional outflow pathway (consisting of the trabecular meshwork and Schlemm’s canal). The discovery that nitric oxide signaling plays a key role in intraocular regulation via its action on the conventional outflow pathway has led to the development of nitric oxide-donating agents that produce significant functional improvements in this pathway. In this continuing medical education activity, expert physicians examine the importance of the nitric oxide pathway in the eye and therapies that target this pathway.