This activity is expired and is no longer available for CME credit.


Challenges in Cryptogenic Stroke: Identifying Candidates for Patent Foramen Ovale Closure

Author(s)/Faculty: Howard C. Herrmann, MD, FACC, MSCAI; John D. Carroll, MD, MSCAI, FACC; Scott E. Kasner, MD, MSCE
Release Date: 4/30/2021Expiration Date: 4/29/2022
Credit Type: CME / CME with ABIM MOCNumber of Credits: 0
Content Type: VideoProvider:
Cryptogenic stroke refers to ischemic brain infarct of undetermined etiology despite extensive clinical evaluation. Approximately 40% of patients who experience cryptogenic stroke are found to have a hole between the left and right atria of the heart called patent foramen ovale (PFO), which is associated with an increased risk of paradoxical thromboembolic stroke. Randomized clinical trial data now support the safety and efficacy of transcatheter PFO closure for secondary stroke prevention. After a period of considerable debate regarding safety and efficacy, updated clinical practice guidelines now recommend PFO closure for appropriately selected patients following evaluation by neurology and cardiology, along with discussion of the procedural risks and benefits. In this expert panel activity, faculty describe diagnostic and classification criteria, explain the link between PFO and embolic stroke, and review strategies for prevention of recurrent stroke in patients with PFO. Faculty also review the latest data on the safety and efficacy of PFO closure and discuss guidelines for applying this data to clinical practice.