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Motor Fluctuations in Parkinson's Disease: Causes, Consequences, and New Choices for Management

Author(s)/Faculty: Rajesh Pahwa, MD; Stuart Isaacson, MD; Daniel E. Kremens, MD, JD
Release Date: 3/19/2019Expiration Date: 3/18/2020
Credit Type: CMENumber of Credits: 0
Content Type: VideoProvider:
Parkinson's disease is a progressive, chronic, neurodegenerative disorder that affects more than 10 million people worldwide. It is canonically regarded as a hypokinetic motor condition, with bradykinesia, resting tremor, and rigidity as its classic features. However, neuropsychiatric and other nonmotor symptoms can have a greater impact on patients’ quality of life. In early disease, the motor symptoms of many patients can be controlled with the use of levodopa. However, many patients gradually experience “Off episodes” in which symptoms reemerge, often in a severe and long-lasting form. This wearing-off effect of treatment can further reduce quality of life, but treatment options are limited. This CME activity will feature a panel discussion with 3 expert clinicians who will assess recent therapeutic updates in the treatment of patients with Parkinson’s disease and the latest strategies to manage patients' Off episodes.