Surgical Delivery Systems That Extend Treatment Intervals for nAMD and DME: Closer Than You Think!

0.75 CME
$0 FEE
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Provider Statement

This continuing medical education activity is provided by Vindico Medical Education

Support Statement

This activity is supported by an educational grant from Genentech, a member of the Roche Group.

Activity Description

Treatment burden and loss of patient adherence due to dosing schedules remain an unmet need in the management of diabetic macular edema (DME) and neovascular age-related macular degeneration (nAMD). Even though current treatment protocols have been refined to extend the time between treatment intervals, many patients are unable to move beyond a 4- to 8-week dosing schedule. Ongoing clinical studies are evaluating gene therapy and sustained delivery devices as potential options to extend treatment intervals while maintaining visual acuity. To achieve optimal efficacy outcomes and safety of these new extended treatment modalities, unique surgical approaches must be utilized. In this CME activity, experts in the field assess emerging surgical delivery systems that have the potential to extend the interval between treatments for patients with DME and nAMD, as well as review novel surgical techniques and procedures to minimize ocular adverse events.

Target Audience

The intended audience for this activity is retina specialists and other health care professionals involved in the management of patients with neovascular age-related macular degeneration and diabetic macular edema.

Learning Objectives

Upon successful completion of this activity, participants should be better able to:

  • Assess emerging surgical delivery systems that allow for the treatment of nAMD and DME over an extended period of time.
  • Evaluate novel surgical and laser techniques and procedures that minimize ocular adverse events when using delivery systems to treat nAMD and DME.

Activity Chair

Margaret A. Chang, MD, MS
Senior Partner
Retinal Consultants of Sacramento
Sacramento, CA


Jordan M. Graff, MD, FACS, FABO
Surgeon & Partner, BDP Eye Center – Retina Division
American Vision Partners (AVP) Medical Executive Team
Clinical Assistant Professor of Ophthalmology
University of Arizona College of Medicine – Phoenix
Clinical Assistant Professor
Creighton University
Phoenix, AZ


Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP


Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation

Vindico Medical Education designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to satisfy the Lifelong Learning and Self-Assessment requirements for the American Board of Ophthalmology’s Continuing Certification program. It is the CME activity provider’s responsibility to submit learner completion information to ACCME for the purpose of granting credit.

Upon successful completion, learners who opt-in by providing their ABO ID and DOB (MM/DD) will earn credits equivalent to the amount of CME credits claimed for the activity.

This enduring material is approved for 1 year from the date of original release, November 19, 2021, to November 18, 2022.

How to Participate in This Activity and Obtain CME Credit

To participate in this CME activity, you must read the objectives, answer the polling and pretest questions, view the content, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 3 of 4 posttest questions correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ certificate.


In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all accredited providers are required to mitigate and disclose to the activity audience the relevant financial relationships of the planners, teachers, and authors involved in the development of accredited content. Individuals have a relevant financial relationship if they have a financial relationship in any amount occurring in the past 12 months with a commercial interest whose products or services are discussed in the accredited activity content over which the individual has control. Relationship information appears below.  

Activity Chair and Faculty report the following relationship(s)

Margaret A. Chang, MD, MS
Consultant: Genentech, RegenxBio
Independent Research Contractor: Allergan, Genentech, Mylan, Novartis, NGM, Opthea, Ophthotech, Regeneron, RegenxBio

Jordan M. Graff, MD, FACS, FABO
Consultant: Genentech/Roche
Speaker for Ineligible Company: Genentech/Roche
Independent Research Contractor: Genentech, Novartis, Regeneron

Reviewer reports the following relationship(s)

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
No relevant financial relationships to disclose.

Vindico Medical Education staff report the following relationship(s)

No relevant financial relationships to disclose.

Signed disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Unlabeled and Investigational Usage

The audience is advised that this continuing medical education activity may contain references to unlabeled uses of US Food and Drug Administration (FDA)–approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2021 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

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