NMOSD: Differentiating New Advances in the Diagnostic and Treatment Armamentarium

1.00 CME
$0 FEE
You've successfully added to your alerts. You will receive an email when new content is published.

Click Here to Manage Email Alerts

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com.

Image of Brain


Provider Statement

This continuing medical education activity is provided by Vindico Medical Education

Support Statement

This activity is supported by an educational grant from Genentech, a member of the Roche Group.

Activity Description

Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disease of the central nervous system that mainly manifests through recurrent attacks of optic neuritis and longitudinally extensive transverse myelitis. Early stages are frequently misdiagnosed. The application of newer diagnostic criteria may facilitate earlier and more accurate diagnosis by assisting neuro-ophthalmologists in the identification of individuals who might otherwise have been diagnosed with idiopathic transverse myelitis, idiopathic optic neuritis, or atypical multiple sclerosis. Treatment options have been limited until recently. Monoclonal antibodies have been used for patients with autoimmune disorders for several years, and their efficacy and safety in patients with NMOSD have been demonstrated. In this educational activity, expert clinicians discuss the burden, diagnosis pathophysiology, and treatment of NMOSD as well as a challenging case.

Target Audience

The intended audience for this activity is neuro-ophthalmologists, ophthalmologists, neurologists, and other health care professionals involved in the management of patients with NMOSD.

Learning Objectives

Upon successful completion of this activity, participants should be better able to:

  • Summarize evidence-based criteria that aids in early detection and staging of NMOSD.
  • Differentiate the mechanisms of action of currently available NMOSD therapeutics to better understand how they can be utilized in individual patients.
  • Assess current evidence pertaining to the safety and efficacy of monoclonal antibodies used in the treatment of NMOSD, including their ability to control acute attacks and prevent future relapses.

Activity Chair

Andrew G. Lee, MD
Chairman of Ophthalmology
Blanton Eye Institute
Houston Methodist Hospital
Clinical Professor of Ophthalmology
University of Texas Medical Branch MD Anderson Cancer Center
Adjunct Professor of Ophthalmology
Baylor College of Medicine
Houston, TX
Professor of Ophthalmology, Neurology, and Neurosurgery
Weill Cornell Medical College
New York, NY
Clinical Professor of Ophthalmology
University of Buffalo, SUNY
Buffalo, NY
Adjunct Professor of Ophthalmology
University of Iowa
Iowa City, IA


John J. Chen, MD, PhD
Professor of Ophthalmology and Neurology
Mayo Clinic
Rochester, MN

Heather E. Moss, MD, PhD
Associate Professor of Ophthalmology, Neurology & Neurological Sciences
Stanford University
Palo Alto, CA


Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP


Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation

Vindico Medical Education designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This enduring material is approved for 1 year from the date of original release, March 23, 2022, to March 22, 2023.

How to Participate in This Activity and Obtain CME Credit

To participate in this CME activity, you must read the objectives, answer the polling and pretest questions, view the content, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 2 of the 3 posttest questions correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ certificate.


Vindico Medical Education adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Activity Chair and Faculty report the following relevant financial relationship(s)

John J. Chen, MD, PhD
Consultant: Roche

Andrew G. Lee, MD
No relevant financial relationships to disclose.

Heather E. Moss, MD, PhD
Advisor: Genentech

Reviewer reports the following relevant financial relationship(s)

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
No relevant financial relationships to disclose.

Vindico Medical Education staff report the following relevant financial relationship(s)

No relevant financial relationships to disclose.

Signed disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Unlabeled and Investigational Usage

The audience is advised that this continuing medical education activity may contain references to unlabeled uses of US Food and Drug Administration (FDA)–approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. © 2022 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

CME Questions?

Contact us at cme@vindicoCME.com