Ace the Case: Utilization of a Molecular Diagnostic Panel in a 73-Year-Old With Community-Acquired Pneumonia

0.25 CME
$0 FEE
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Utilization of a Molecular Diagnostic Panel in a 73-Year-Old With Community-Acquired Pneumonia


Provider Statement

This continuing medical education activity is provided by vindico

Support Statement

This activity is supported by an educational grant from BioFire Diagnostics, LLC.

Activity Description

Bacterial, viral, fungal, or parasitic infections of the respiratory tract, blood stream, or central nervous system (CNS) often present with overlapping or nonspecific clinical findings, posing significant diagnostic challenges. Rapid and accurate detection of the causative pathogen is critical for timely intervention. Despite important advances in diagnostic technologies, many patients with suspected infections receive empiric or broad-spectrum antimicrobial agents while awaiting the results of standard microbiologic testing, which can contribute to prolonged or unnecessary use of these agents and promote drug resistance. Syndromic testing using panel-based molecular diagnostics can provide rapid and sensitive detection of pathogens in positive blood cultures, respiratory specimens, and cerebrospinal fluid, enabling earlier initiation of pathogen-directed interventions and de-escalation of unnecessary therapy. Multiplex molecular panels have led to paradigm shifts in clinical microbiology, and education is needed to ensure the appropriate utilization as well as interpretation of results. In this educational Ace the Case web series, experts present clinical cases to examine the role of syndromic testing for the early and accurate diagnosis of various infectious diseases. Faculty will review the sensitivity and specificity of available multiplex panels for the detection of pathogens in pneumonia, blood stream infections, and CNS infections. 

Target Audience

The intended audience for this activity is infectious disease specialists, pediatricians, emergency medicine physicians, and other health care professionals involved in the management of patients with infectious diseases.

Learning Objective(s)

Upon successful completion of this activity, participants should be better able to:

  • Examine the role of syndromic testing for the early and accurate diagnosis of various infectious diseases.
  • Assess the sensitivity and specificity of multiplex panels and assays used for the diagnosis of pneumonia, blood stream infections, infections of the central nervous system, and other infectious diseases.


Amanda Harrington, PhD, D(ABMM)
Clinical Microbiology Laboratory
Loyola Medicine
Associate Professor
Loyola University Chicago
Chicago, IL


Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP


Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Credit Designation

Vindico Medical Education designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to

abp moc0.25 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program.

It is the CME activity provider's responsibility to submit learner completion information to ACCME for the purpose of granting ABP MOC credit.

This enduring material is approved for 1 year from the date of original release, September 30, 2021, through September 29, 2022.

How to Participate in This Activity and Obtain CME Credit

To participate in this CME activity, you must read the objectives, answer the polling and pretest questions, view the content, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering the posttest question correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ Certificate.


In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all accredited providers are required to mitigate and disclose to the activity audience the relevant financial relationships of the planners, teachers, and authors involved in the development of accredited content. Individuals have a relevant financial relationship if they have a financial relationship in any amount occurring in the past 12 months with a commercial interest whose products or services are discussed in the accredited activity content over which the individual has control. Relationship information appears below.

Faculty reports the following relationship(s)

Amanda Harrington, PhD, D(ABMM)
Contracted Research: BioFire

Reviewer reports the following relationship(s)

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
No relevant financial relationships to disclose.

Vindico Medical Education staff report the following relationship(s)

No relevant financial relationships to disclose.

Signed disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Unlabeled and Investigational Usage

The audience is advised that this continuing medical education activity may contain references to unlabeled uses of US Food and Drug Administration (FDA)–approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2021 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

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