Flu in the Rheum! Managing Influenza Infection

1.25 CME
$0 FEE
Flu in the Rheum! Managing Influenza Infection


Provider Statement

This continuing medical education activity is provided by Vindico Medical Education

Support Statement

This activity is supported by an educational grant from Genentech, Inc.

Activity Description

Influenza places a substantial burden on the health of both children and adults in the United States each year. While immunization helps to prevent flu infection, there is a need for improved treatments, preventative measures, and better mitigation for the impact associated with a pandemic, especially in high-risk patients who have comorbid illnesses or who are immunocompromised. In particular, patients with rheumatic disorders are highly vulnerable to infections because of abnormalities in their immune system, and the immunosuppressive effects of their medications. They are a high-risk group for influenza virus infection as well as for complications from the virus. Therefore, it is important that rheumatologists and internists are competent in their management of patients who have a rheumatic disease and are either exposed to or contract influenza. In this continuing educational activity, expert clinicians will discuss the latest updates on diagnosing and treating influenza.

Target Audience

The intended audience for this activity is rheumatologists and other health care professionals involved in the management of patients with influenza.

Learning Objectives

Upon successful completion of this educational activity, participants should be better able to:

  • Review the burden and complications resulting from influenza and how they may affect patients who are immunocompromised and/or immunosuppressed.
  • Utilize evidence-based algorithms when interpreting the results of diagnostic tests for influenza.
  • Incorporate the most appropriate influenza treatment regimen in patients at high risk for complications, based on evidence of the regimen’s safety and efficacy in these patients.

Activity Chair

Leonard H. Calabrese, DO
Professor of Medicine
Cleveland Clinic Lerner College of Medicine
Case Western Reserve University
R.J. Fasenmyer Chair of Clinical Immunology
Cleveland Clinic
Cleveland, OH


Cassandra Calabrese, DO
Rheumatology and Infectious Disease
Cleveland Clinic Foundation
Cleveland, OH

Paul E. Sax, MD
Clinical Director, Division of Infectious Diseases
Brigham and Women's Hospital
Professor of Medicine
Harvard Medical School
Boston, MA

Medical Writer

Valerie Zimmerman, PhD


Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP


Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Credit Designation

Vindico Medical Education designates this enduring material for a maximum of 1.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

This enduring material is approved for 1 year from the date of original release, February 1, 2021, to February 1, 2022.

How to Participate in This Activity and Obtain CME Credit

To participate in this CME activity, you must read the objectives, answer the pretest questions, view the content, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 7 of the 10 posttest questions correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ certificate.


In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all accredited providers are required to mitigate and disclose to the activity audience the relevant financial relationships of the planners, teachers, and authors involved in the development of accredited content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the past 12 months with a commercial interest whose products or services are discussed in the accredited activity content over which the individual has control. Relationship information appears below.  

The articles in this monograph were composed by medical writer Valerie Zimmerman, PhD, based on the presentations of Dr. Leonard Calabrese, Dr. Casandra Calabrese and Dr. Paul Sax during a live virtual symposium during the ACR Convergence 2020, on November 7, 2020. The monograph has been approved by each of the authors individually as an accurate representation of their presentation.

Activity Chair and faculty report the following relationship(s)

Leonard H. Calabrese, DO
Consulting Fee: AbbVie, Amgen, Bristol-Myers Squibb, Crescendo, Genentech, Gilead, GlaxoSmithKline, Horizon, Janssen, Kiniksa, Lilly, Pfizer, Sanofi-Regeneron, UCB
Speakers Bureau: AbbVie, Bristol-Myers Squibb, Crescendo, Genentech, Horizon, Sanofi, UCB

Cassandra Calabrese, DO
Consulting Fee: AbbVie
Speakers Bureau: Regeneron

Paul E. Sax, MD
Consulting Fee: Gilead, GlaxoSmithKline/ViiV, Janssen, Merck
Contracted Research: Gilead, GlaxoSmithKline/ViiV, Merck
Editorial Positions: Medscape, New England Journal of Medicine Journal Watch, Open Forum Infectious Diseases, UpToDate

Medical Writer reports the following relationship(s)

Valerie Zimmerman, PhD
No relevant financial relationships to disclose.

Reviewer reports the following relationship(s)

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
No relevant financial relationships to disclose. 

Vindico Medical Education staff report the following relationship(s)

No relevant financial relationships to disclose.

Signed disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Unlabeled and Investigational Usage

The audience is advised that this continuing medical education activity may contain references to unlabeled uses of US Food and Drug Administration (FDA)-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non—FDA-approved or investigational use of products/devices.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2021 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

CME Questions?

Contact us at cme@vindicoCME.com