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IBECEXPERT VIDEOCME

Treating TNF Non-responders

Author(s)/Faculty: Jonathan Kay, MD; Leonard H. Calabrese, DO
Release Date: 8/23/2016Expiration Date: 8/22/2017
Credit Type: CMENumber of Credits: 0
Content Type: VideoProvider:
Rheumatoid arthritis (RA) is a progressive and painful systemic inflammatory disease that preferentially attacks the synovium of the joint leading to joint destruction, debility, and deformity. Increased understanding of the underlying pathophysiology of RA has made a remarkable difference in its treatment and prognosis. Numerous therapeutic agents with diverse targets and mechanisms have been added to the RA armamentarium, allowing for intervention at various stages in the pathogenic process of the disease. By understanding the underlying immunologic mechanisms driving RA progression, clinicians involved in the management of patients with RA will be better equipped to evaluate the clinical and pharmacologic safety, as well as efficacy profiles of current and emerging therapies. In this series of Curbside Consults, experts in RA will present cases from their own practices and have a collegial discussion about the challenges introduced by the cases, with a focus on key concepts in immunology as they relate to clinical care.