CME Information
Provider Statement: This continuing nursing education activity is co-provided by 
and 
.
Support Statement: This activity is supported by educational grants from Bristol-Myers Squibb, Lilly, and Pfizer.
There is no non-commercial support for this activity.
Education activities are distinguished as separate from endorsement of commercial products. When commercial products are displayed, participants will be advised that accredited status as a provider refers only to its continuing education activities and does not imply ANCC Commission on Accreditation endorsement of any commercial products.
Target Audience: The intended audience for this activity is advanced practice nurses, rheumatology nurses, and infusion nurses involved in the treatment of patients with rheumatoid arthritis (RA).
Purpose/Learning Objectives: Upon successful completion of this educational activity, participants should be better able to:
- Describe the underlying principles of innate and adaptive immunity as they contribute to understanding the mechanism of action of existing and developing immune-based therapies including anti-cytokine therapies (TNF, IL-6, IL-17, and others); T-cell- and B-cell-directed therapies; anti-checkpoint-based therapies; small molecules; anti-sense therapies; immunoregulatory-based therapies; and others.
- Examine the underlying principles of innate and adaptive immunity as they contribute to the pathophysiologic basis of autoimmune and autoinflammatory diseases like RA.
- Explain the clinical and immunologic progression of RA from asymptomatic autoimmunity to pre-RA and RA and relate the role of anti-citrullinated protein antibodies (ACPAs) and gene interactions to this process.
- Describe recent advances in innate and adaptive immunity that contribute to the understanding of immunopathogenesis, immunodiagnostics, and selection of immune-based therapies including:
- Genetics and epigenetics in the immunopathogenesis in autoimmune and autoinflammatory diseases.
- The microbiome and microvirome and their relationship to the integrated immune response and immunopathogenesis.
- The concept of immunologic checkpoint-directed therapies as a basis for cancer treatment and autoimmune and autoinflammatory complications relevant to rheumatologists.
Moderator:
Iris Zink, MSN, RN, ANP-BC
Department of Rheumatology
Beals Institute
RNS Board Member, President
Lansing, MI
Faculty:
Leonard H. Calabrese, DO
Professor of Medicine
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
Director of the R. J. Fasenmyer Center for Clinical Immunology
Cleveland Clinic
Cleveland, OH
Elizabeth Kirchner, CNP, MSN
Department of Rheumatologic and Immunologic Disease
Cleveland Clinic
Cleveland, OH
Grace C. Wright, MD, PhD, FACR
Clinical Associate Professor of Medicine
New York Langone Medical Center, Division of Rheumatology
Association of Women in Rheumatology, President
New York, NY
Nurse Planner:
Barbara Niedz, PhD, RN, CPHQ
Reviewer:
Ronald Codario, MD, FACP, FNLA, RPVI, CHCP (Recertification review on 11/6/2017 and 11/19/2018)
Accreditation:
Vindico Medical Education, LLC is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation.
Credit Designation:
Vindico Medical Education will provide 0.25 contact hours for nurses.
This enduring material was originally approved for 1 year from the date of original release, November 22, 2016 to November 21, 2017. It has since been recertified for 2 additional years and will now expire on November 21, 2019.
How to Participate in this Activity and Obtain CNE Credit:
To participate in this CNE activity, you must read the objectives, answer the pretest questions, watch the presentation, complete the posttest, and fill-in the evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering the posttest question correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue a Learner-Paced Contact Hours Certificate.
Disclosures:
In accordance with the American Nurses Credentialing Center’s Standards for Commercial Support, all CNE providers are required to disclose to the activity audience the relevant financial relationships of the planners, faculty, and reviewers involved in the development of CNE content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the last 12 months with a commercial interest whose products or services are discussed in the CNE activity content over which the individual has control. Relationship information appears above.
Moderator, Faculty, and Steering Committee report the following relationship(s) which are accurate at the time of original content release (November 22, 2016):
Iris Zink, MSN, RN, ANP-BC
Speakers Bureau: AbbVie, Bristol-Myers Squibb, Crescendo
Leonard H. Calabrese, DO
Consulting Fee: GlaxoSmithKline, Janssen, Pfizer, Sanofi
Speakers Bureau: AbbVie, Bristol-Myers Squibb, Crescendo, Genentech, Janssen
Joseph E. Craft, MD
Non-CME Services Fees: Bristol-Myers Squibb, MedImmune
John J. Cush, MD
Clinical Investigator: AbbVie, AstraZeneca, Celgene, Janssen, Novartis, Pfizer
Consulting Fee: AbbVie, Amgen, Bristol-Myers Squibb, Celgene, Genentech, Janssen, Lilly, Novartis, Pfizer, UCB
Elizabeth Kirchner, CNP, MSN
Consulting Fee: Pfizer, Sanofi
Speakers Bureau: Crescendo
William F.C. Rigby, MD
Consulting Fee: Bristol-Myers Squibb, Lilly, Pfizer, Roche
Non-CME Services Fees: Bristol-Myers Squibb
Contracted Research: Amgen, Bristol-Myers Squibb, Pfizer, Roche
Sergio Schwartzman, MD
Speakers Bureau: AbbVie, Crescendo, Genentech, Hospira, Janssen, Novartis,
Pfizer
Stock Ownership: Amgen, Gilead, Medtronic, Pfizer
Consulting Fee: AbbVie, Crescendo, Epirus, Genentech, Hospira, Janssen,
Novartis, Pfizer, Regeneron
Board Member: Discus-Analytics National Psoriasis Foundation
Scientific Advisory Board Member: Bioscience, Crescendo
Gregg Silverman, MD
Consulting Fee: Bristol-Myers Squibb, Genentech
Speakers Bureau: Genentech
Grace C. Wright, MD, PhD, FACR
Consulting Fees: AbbVie, Bristol-Myers Squibb, Crescendo, Eli Lilly, Genentech, Janssen, Pfizer
Speakers Bureau: AbbVie, Amgen, Bristol-Myers Squibb, Crescendo, Genentech, Mallinckrodt, Novartis
Nurse Planner reports the following relationship(s):
Barbara Niedz, PhD, RN, CPHQ
No relevant financial relationships to disclose.
Reviewer reports the following relationship(s):
Ronald Codario, MD, FACP, FNLA, RPVI, CHCP
No relevant financial relationships to disclose.
Vindico Medical Education and the Rheumatology Nurses Society report the following relationship(s):
No relevant financial relationships to disclose.
Signed disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.
Unlabeled and Investigational Usage:
The audience is advised that this continuing medical education activity may contain references to unlabeled uses of FDA-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non-FDA approved or investigational use of products/devices.
Copyright Statement:
Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2016 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.
CNE Questions?
Contact us at cme@vindicoCME.com