COVID-19 PrEP in Immunocompromised Patients: Prevention Better Than Cure?

Author(s)/Faculty: Leonard H. Calabrese, DO; Myron Cohen, MD; Myron Levin, MD
Release Date: 12/15/2022Expiration Date: 12/14/2023
Credit Type: CMENumber of Credits: 1
Content Type: LectureProvider:
The COVID-19 pandemic has led to a health care crisis with widespread global morbidity and mortality, spurring unprecedented levels of research for effective treatment and prevention strategies. Immunocompromised individuals are at increased risk for breakthrough SARS-CoV-2 infection, high symptomatic burden, and progression to severe COVID-19. Additionally, immune suppression due to certain medical conditions or therapies may limit the ability to mount a sufficient immune response with vaccination. Disease prevention is therefore of great importance in this patient population. In this educational activity, faculty in immunology and infectious diseases outline the rationale for using COVID-19 preexposure prophylaxis (PrEP) therapy in immunocompromised patients, reviewing the latest clinical evidence on its safety and efficacy. Experts will provide guidance for identifying patients who may benefit from COVID-19 PrEP and summarize strategies to educate patients and practitioners on the outpatient management of COVID-19 in this vulnerable group.